徐龙教授一直致力于固有免疫细胞在肝脏急慢性损伤疾病中的免疫机制研究，近几年重点研究嗜酸性粒细胞在肝脏疾病、免疫细胞对话中的作用研究。代表作发表在Journal of Hepatology，Gut，Hepatology（2篇），PNAS，CMGH等国际知名期刊上，主持国家自然科学基金、国家重点研发专项，安徽省高校杰出青年人才项目等十余项。安徽省省级人才项目获得者。

个人简历：

2002.09 - 2006.07   安徽医科大学, 生物技术, 学士

2006.09 - 2011.05   中国科学技术大学, 细胞生物学, 博士

2011.05 - 2013.12   中国科学技术大学，博士后

2013.12 - 2015.08   安徽医科大学, 基础医学院, 讲师

2015.08 - 2022.12   安徽医科大学, 基础医学院, 副教授，硕士生导师

2019.11 - 2021.10   UT Health Science Center at Houston，访问学者

2022.12 - 至今         安徽医科大学, 基础医学院, 教授，博士生导师

1. 国家自然科学基金面上项目，82270640，嗜酸性粒细胞通过分泌IL-4/IL-13保护急性肝损伤并促进肝修复，2023/01-2026/12，52万元；（在研）

2. 国家重点研发计划“发育编程及其代谢调节专项”，2023YFA180800，髓系细胞发育与代谢在脂肪性肝病中的调控作用及干预研究，2023/12-2028/11，1900万元（个人经费110万元，项目骨干）；（在研）

3. 安徽省高校杰出青年人才项目，2022AH020051，固有免疫与肝脏疾病，2023/01-2025/12，100万元；（在研）

4. 安徽医科大学科研提升计划，2023xkjT006，嗜酸性粒细胞-巨噬细胞互作在脂肪肝缺血再灌注损伤修复中的机制研究，2024/01-2026/12，30万元；（在研）

5.安徽医科大学基础医学院“优秀中青年学术带头人培养计划”，2022YPJH101，2022/06-2025/05，20万元。（在研）

6. 国家自然科学基金面上项目，81873570，乙型肝炎病毒慢性感染加剧酒精性肝病以及天然杀伤 （NK）/NKT 细胞的免疫调节机制，2019/01-2022/12，57万元；（已结题）

7. 国家自然科学基金青年项目，81401281，MHCⅡ类分子在NK细胞功能发育中的作用机制，2015/01-2017/12，23万元；（已结题）

1. Xu L#, Yang Y#, Wen YK, Jeong JM, Emontzpohl C, Atkins CL, Sun ZL, Poulsen KL, Hall DR, Bynon JS, Gao B, Lee WM, Rule J, Jacobsen EA, Wang H*, and Ju C*. Hepatic recruitment of eosinophils and their protective function during acute liver injury. J Hepatol. 2022; 77(2):344-352. (IF: 28)

2. Xu L#, Yang Y#, Jiang JL, Wen YK, Jeong JM, Emontzpohl C, Atkins CL, Kangho K, Jacobsen EA, Wang H*, and Ju C*. Eosinophils protect against acetaminophen-induced liver injury through cyclooxygenase-mediated IL-4/IL-13 production. Hepatology. 2023; 77(2):456-465. (IF: 15.5)

3. Yang Y#, Xu L#, Atkins CL, Kuhlman L, Zhao J, Jeong JM, Wen YK, Moreno N, Kim KH, An YA, Wang FF, Bynon S, Villani V, Gao B, Brombacher F, Harris R, Eltzschig HK,  Jacobsen EA, Ju C*. Novel IL-4/HB-EGF-dependent crosstalk between eosinophils and macrophages controls liver regeneration after ischaemia and reperfusion injury. Gut. 2024; doi: 10.1136. (IF: 24.5，Co-first author)

4. Cheng C#, Zhang Q#, Li Y#, Jiang JL, Xie LX, Shen HY, Wu DQ, Zhang HJ, Zhang HR, Wang X, Xu JJ, Wu HY, Gui L, Li B, Ju C, Peng H, Yin S*, and Xu L*. Interplay between liver type 1 innate lymphoid cells and NK cells drives the development of alcoholic steatohepatitis. Cell Mol Gastroenterol Hepatol. 2023; 23;15(1):261–274. (IF: 7.9)

5. Xu L, Yin WW, Sun R, Wei HM, and Tian ZG*. Liver type I regulatory T cells suppress germinal center formation in HBV-tolerant mice. Proc Nati Acad Sci U S A. 2013; 110:16993-16998. (IF: 10.8)

6. Xu L#, Yin WW#, Sun R, Wei HM, and Tian ZG*. Kupffer cell-derived IL-10 plays a key role in maintaining humoral immune tolerance in HBV-persistent mice. Hepatology. 2014; 59:443-452. (IF: 15.5)

7. Xu L#, Zhang Y#, Zhang RJ, Zhang H, Song P, Ma T, Li Y, Wang X, Hou X, Li Q, Xu JG, Gao XP*, and Shen CL*. Elevated plasma BDNF levels are correlated with NK cell activation in patients with traumatic spinal cord injury. Int Immunopharmacol. 2019; 74:105722. (IF: 5)

8. Li Y#, Wang X#, Cheng C, Jiang SL, Ma T, and Xu L*. Absence of MHC class II molecules promotes natural killer cells activation in mice. Int Immunopharmacol. 2020; 88:106888. (IF: 5)

9. Jiang S#, Zhu Y#, Cheng C, Li Y, Ma T, Peng ZW, Li Q, Xu JG, and Xu L*. NK cells contribute to hepatic CD8 + T cell failure in hepatitis B virus-carrier mice after alcohol consumption. Virus Res. 2020; 2;286:198085. (IF: 3.2)

10. Wang X#, Zhu J#, Zhang Y, Li Y, Ma T, Li Q, Xu JG, and Xu L*. The doses of plasmid backbone plays a major role in determining the HBV clearance in hydrodynamic injection mouse model. Virol J. 2018; 21;15(1):89-97. (IF: 3.8)

11. Ma T#, Li Y#, Zhu Y, Jiang SL, Cheng C, Peng ZW, and Xu L*. Differential Metabolic Pathways and Metabolites in a C57BL/6J Mouse Model of Alcoholic Liver Disease. Med Sci Monit. 2020; 8;26:e924602. (IF: 2.5)

12. Xu L, Wang H. A dual role of inflammation in acetaminophen-induced liver injury. Liver Res. 2023;7(1):9-15. (IF: 2)

13. Shen H#, Zhou L#, Zhang H#, Yang Y, Jiang L, Wu D, Shu H, Zhang H, Xie L, Zhou K, Cheng C, Yang L, Jiang J, Wang S, Han Y, Zhu J, Xu L, Liu Z*, Wang H*, Yin S*. Dietary fiber alleviates alcoholic liver injury via Bacteroides acidifaciens and subsequent ammonia detoxification. Cell Host Microbe. 2024; S1931-3128(24)00226-9. (IF: 22.1)

14. Wen Y, Emontzpohl C, Xu L, Atkins CL, Jeong JM, Yang Y, Kim K, Wu C, Akira S, Ju C*. Interleukin-33 facilitates liver regeneration through serotonin-involved gut-liver axis. Hepatology. 2023; 77(5):1580-1592. (IF: 15.5)

15. Hou X#, Liu Q#, Gao Y#, Yong L, Xie H, Li W, Zhou Y, Liu J, Feng L, Xu L, Shen Y, Wang H*. Mesencephalic astrocyte-derived neurotrophic factor reprograms macrophages to ameliorate acetaminophen-induced acute liver injury via p38 MAPK pathway. Cell Death Dis. 2022; 13(100). (IF: 8.6)

16. Wang Y#, Yang Y#, Wang M#, Wang S, Jeong JM, Xu L, Wen Y, Emontzpohl C, Atkins CL, Duong K, Moreno NF, Yuan X, Hall DR, Dar W, Feng D, Gao B, Xu Y, Czigany Z, Colgan SP, Bynon JS, Akira S, Brown JM, Eltzschig HK, Jacobsen EA, Ju C*. Eosinophils attenuate hepatic ischemia reperfusion injury in mice through ST2-dependent IL-13 production, Sci Transl Med. 2021; 13(579):eabb6576. (IF: 16.9)

17. Li M, Sun R, Xu L, Yin W, Chen Y, Zheng X, Lian Z, Wei H, Tian Z*. Kupffer Cells Support Hepatitis B Virus-Mediated CD8+ T Cell Exhaustion via Hepatitis B Core Antigen-TLR2 Interactions in Mice. J Immunol. 2015; 195(7):3100-9. (IF: 4.2)

18. Li FL#, Wei HR#, Wei HM, Gao YF, Xu L, Yin WW, Sun R, Tian ZG*. Blocking the natural killer cell inhibitory receptor NKG2A increases activity of human natural killer cells and clears hepatitis B virus infection in mice. Gastroenterology. 2013; 144(2):392-401. (IF: 25.2)

19. Yin W, Xu L, Sun R, Wei H, Tian Z*. Interleukin-15 suppresses hepatitis B virus replication via IFN-β production in a C57BL/6 mouse model. Liver Int. 2012; 32(8):1306-14. (IF: 6.3)

注：上述影响因子IF均为期刊近5年平均IF