程娟，硕士研究生导师, 博士。主要从事与生物节律与睡眠，孤独症等神经退行性疾病的发病机制研究。主持国家自然基金青年项目1项，省级自然基金项目2项，参与国家自然基金面上项目和青年项目各一项，主持省级、院级质量工程各1项，参与并完成省级质量工程3项，优秀完成校级质量工程1项，连续三年获得基础医学院青年教师基本功大赛二、三等奖。迄今，已在Front Pharmacol， JBR, Cell Research等期刊上发表SCI收录论文15余篇。

教育和进修经历

2021.06 - 2022.06  中国科学院深圳先进技术研究院  访问学者，合作导师：鲍进

2014.09 - 2017.07  安徽医科大学, 药理学, 博士, 导师: 王烈成、薛天（中国科学技术大学）、鲍进（中国科学技术大学）

2010.09 - 2013.07  安徽医科大学, 生理学, 硕士, 导师: 王烈成，张晨(北京大学）

2005.09 - 2010.07  安徽医科大学, 临床药理学, 学士

1. 安徽省基金面上项目, 2308085MC83, 安徽省科技厅, 2023.4-2026.4, 在研,主持;

2. 安徽省高校重点项目, 2022AH050783, 安徽省教育厅, 2022.12-2024.12, 在研, 主持;

3. 安徽省转化医学研究院科研基金项目，2023zhyx-C71，2024.1.1-2026.12.31，在研, 基础合作者;

4. 国家自然科学基金委员会青年项目, 31800997, 2019.1-2021.12, 结题, 主持;

5. 国家自然科学基金委员会面上项目，81971236，2020.1-2023.12,结题，参与;

6. 国家自然科学基金委员会青年项目, 81801064, 2019.1-2021.12, 结题, 参与;

7. 安徽省高等学校自然科学研究重点项, KJ2019A0284, 2019.7.1-2021.7.1，结题, 参与；

8. 安徽医科大学博士科研资助基金，XJ201727，结题，主持；

9. 院级质量工程：2020jxxcpj001，结题，主持；

10. 省级质量工程，2021kcszsfkc212，结题，主持；

11. 省级质量工程, 2021xnfzxm052, 在研，参与。

论文与专著（第一作者*，通讯作者#）

1. Zhang Y, Li J, Li Y, Wang W, Wang D, Ding J, Wang L, Cheng J^#. Dexmedetomidine Promotes NREM Sleep by Depressing Oxytocin Neurons in the Paraventricular Nucleus in Mice. Neurochem Res. 2024 Jul 30. doi: 10.1007/s11064-024-04221-w. Epub ahead of print.

2. Chen L, Chen C, Jin Q, Liang Y, Wu J, Zhang P, Cheng J^#, Wang L^#. Efferent pathways from the suprachiasmatic nucleus to the horizontal limbs of diagonal band promote NREM sleep during the dark phase in mice. BMC Neurosci. 2024;25(1):34. 

3. Li G, Li Q, Ping M, Jiao Z, Wang X, Cheng J^#, Guo J^#, Cheng Y^#. SLAMF8 can predict prognosis of pan-cancer and the immunotherapy response effectivity of gastric cancer. Aging (Albany NY). 2024 May 22;16(10):8944-8964.

4. Fan S, Cheng X, Zhang P, Wang Y, Wang L^#, Cheng J^#. The α2 Adrenoceptor Agonist and Sedative/Anaesthetic Dexmedetomidine Excites Diverse Neuronal Types in the Ventrolateral Preoptic Area of Male Mice. ASN Neuro. 2023 Jan-Dec;15:17590914231191016. 

5. Fan S, Jin Q, Zhang P, Xu D, Cheng J^#, Wang L^#. Isoliquiritigenin modulates the activity of LTS and non-LTS cells in the ventrolateral preoptic area via GABAA receptors. Heliyon. 2023 Oct 12;9(10):e20620. 

6. Xu D, Zhang Y, Feng J, Fu H, Li J, Wang W, Li Z, Zhang P, Cheng X, Wang L, Cheng J^#. Activation of the PACAP/PAC1 Signaling Pathway Accelerates the Repair of Impaired Spatial Memory Caused by an Ultradian Light Cycle. ASN Neuro. 2023 Jan-Dec;15 

7. Zhang XW, Chen L, Chen CF, Cheng J, Zhang PP, Wang LC. Dexmedetomidine modulates neuronal activity of horizontal limbs of diagonal band via α2 adrenergic receptor in mice. BMC Anesthesiol. 2023 Oct 2;23(1):327. doi: 10.1186/s12871-023-02278-8. 

8. Yang W, Li H, Cheng Z, Lu Y, Li W, Feng J, Wang L, Cheng J^#.  Dex modulates the balance of water-electrolyte metabolism by depressing the expression of AVP in PVN. Front Pharmacol. 2022 Aug 23;13:919032. 

9. Wang Y, Yang W, Zhang P, Ding Z, Wang L, Cheng J^#. Effects of light on the sleep-wakefulness cycle of mice mediated by intrinsically photosensitive retinal ganglion cells. Biochem Biophys Res Commun. 2022 Jan 11;592:93-98. doi: 10.1016/j.bbrc.2022.01.023. Epub ahead of print. PMID: 35033872.

10. Yue Xu^(#), Ya-Nan Wang^(#), Guang-An Tong^(#), Lin Li, Juan Cheng, Le-sha Zhang, Qi Xu, Lie-cheng Wang^(*), Ping-ping Zhang^(*). Expression of SH3 and Multiple Ankyrin Repeat Domains Protein 3 in Mouse Retina. Frontiers Cellular Neuroscience. 2022; 16:795668. doi: 10.3389/fncel.2022.795668

11. Cheng XQ*, Cheng J*, Zhou YN, Zuo YM, Liu XS, Gu EW, Xu GH. Anti-nociceptive Effects of Dexmedetomidine Infusion Plus Modified Intercostal Nerve Block During Single-port Thoracoscopic Lobectomy: A Double-blind, Randomized Controlled Trial. Pain Physician. 2021 Aug;24(5):E565-E572.

12. Cheng P, Tian X, Tang W, Cheng J, Bao J, Wang H, Zheng S, Wang Y, Wei X, Chen T, Feng H, Xue T, Goda K, He H. Direct control of store-operated calcium channels by ultrafast laser. Cell Res. 2021 Jul;31(7):758-772.  

13. Fan Wu(#), Shuo Wu(#), Qiu-Qi Gui, Kai-Xin Tang, Qi-Qi Xu, Yue Tao, Mei-Xuan Chen, Juan Cheng, Lie-Cheng Wang(*), Le-Sha Zhang(*). Blue light insertion at night is involved in sleep and arousal-promoting response delays and depressive-[like] emotion in mice. Bioscience Reports. 2021; 41(3):BSR20204033. doi: 10.1042/BSR20204033 (期刊论文)

14. Cheng J*, Wu F*, Zhang M, Ding D, Fan S, Chen G, Zhang J, Wang L. The Interaction Between the Ventrolateral Preoptic Nucleus and the Tuberomammillary Nucleus in Regulating the Sleep-Wakefulness Cycle. Front Neurosci. 2020 Dec 14;14:615854.  

15. Chen L, Yang ZL, Cheng J, Zhang PP, Zhang LS, Liu XS, Wang LC. Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABA_A receptors. Acta Pharmacol Sin. 2019 Jun;40(6):755-761. 

16. Cheng J, Huang X, Liang Y, Xue T, Wang L, Bao J. Plasticity of Light-induced Concurrent Glutamatergic and GABAergic Quantal Events in the Suprachiasmatic Nucleus. J Biol Rhythms. 2018 Feb;33(1):65-75.

17. Li Z, You Z, Li M, Pang L, Cheng J, Wang L. Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy. Neurosci Bull. 2017 Jun;33(3):273-280.  

18. Cheng J*, Dong J*, Cui Y*, Wang L, Wu B, Zhang C. Interacting partners of AMPA-type glutamate receptors. J Mol Neurosci. 2012 Oct;48(2):441-7. 

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